The Protocol
A 12-week longitudinal internal pilot observing measurable change in biomarkers following targeted parasympathetic activation.
Methodology
Protocol NSR-2026 combines continuous autonomic monitoring with a structured, multi-modal intervention stack. Each participant acts as their own longitudinal control: we measure before, during, and after the intervention period, then correlate biomarker shifts with autonomic metrics.
Timeline
Comprehensive Baseline
- 47-marker biomarker panel
- Continuous HRV monitoring (wearable + clinical-grade ECG)
- Sleep architecture assessment
- Cortisol awakening response profiling
- Subjective wellbeing and recovery scoring
Targeted Intervention
- Sensory deprivation float therapy sessions
- Contrast therapy (sauna + cold plunge)
- AI-guided breathwork and vagal tone training
- Personalized recovery protocol adjustments
- Weekly biometric check-ins
Intensive Measurement
- Repeat biomarker panel
- HRV trend analysis
- Sleep quality comparison
- Inflammatory marker tracking
- Adherence and tolerability review
Analysis & Reporting
- Cross-correlation of biomarker shifts
- Personalized recovery profile
- Aggregate cohort insights
- Publication-ready anonymized data set
- Optional continuation planning
Intervention Stack
Sensory Deprivation
Float therapy to reduce sympathetic load and amplify parasympathetic tone.
Contrast Therapy
Deliberate thermal stress via sauna and cold plunge to build autonomic resilience.
AI-Guided Breathwork
Real-time biometric feedback drives personalized breathing protocols.
Biomarker Mapping
Continuous HRV, sleep, and inflammatory marker tracking.
Frequently Asked Questions
Is Protocol NSR-2026 a clinical trial?+
No. Protocol NSR-2026 is an internal observational pilot, not a registered clinical trial. It is designed to generate real-world biometric signal and inform future research directions.
Who is eligible to participate?+
Adults 21–65 who are generally healthy and able to commit to the 12-week program. Participants with certain medical conditions or medications may be excluded after eligibility screening.
What does the program cost?+
As an internal pilot, qualified participants receive protocol access at a subsidized research rate. Full pricing and inclusions are shared during the eligibility call.
Where does the program take place?+
Assessments and interventions are conducted at the SoliVana Research Institute in Redwood City, CA, with daily biometric monitoring completed remotely via provided wearables.
Will my data be shared?+
Individual data is never sold. Anonymized aggregate data may be used for internal analysis or publication. See our Privacy Policy for full details.
Enrollment is limited and subject to eligibility screening.